Is there a connection between the condition of the oral cavity (its mucous membranes) with the mental state, well-being of the patient? British Society of Periodontists (BSP) Stress is one of the risk factors for the development of a number of oral diseases, since it affects both the general condition of patients and the periodontal disease. Stress can have both behavioral and physiological consequences. People experiencing a stressful period in their lives may be more likely to smoke, neglect routine oral hygiene, and skip routine dental visits, which increases the risk of developing periodontitis. There is a relationship between stress and periodontitis. associated with the body's immune response in the patient Cortisol, widely known as the body's stress hormone, increases the growth of porphyromonas gingivalis, as well as chronic stress, leads to increased levels of cytokines and other inflammatory mediators, which leads to the development of oral diseases58% of patients with eating disorders have clinical signs of erosion, which is the progressive loss of dental hard tissue as a result of a chemical process not related to bacteria. Self-induced vomiting, characteristic of bulimia, but also seen in other eating disorders such as anorexia, is usually characterized by these changes in the condition of the teeth. Increased use of alcohol and tobacco. , often seen in people with depression, can also cause erosion from gastroesophageal reflux. Patients living with OCD may feel an urge to do activities such as repetitive brushing of teeth. Some patients who fear infection may be too concerned about repeatedly washing their hands to washing hair or brushing teethPatients would actually fall into the high risk categories for caries and periodontal disease. Loss of interest affects oral and dental health because those who previously enjoyed good oral hygiene lose interest in personal hygiene, which is why tooth decay is the most common problem oral and dental health Gingivitis, xerostomia, oral candidiasis, lesions of the oral cavity and temporomandibular joint Xerostomia, are the result of taking antidepressants Increased expression of α1-adrenergic receptors (α1-ARs) in the blood serum and saliva in lesions of the oral mucosa Increased cortisol levels in saliva , which indicates a disruption of the hypothalamic-pituitary axis α1-adrenergic receptors and cortisol are responsible for a significant anti-inflammatory role. Chronic anxiety leads to dysregulation of the production of steroids by the adrenal cortex, a decrease in the production of some of the main precursors for the synthesis of neuroactive steroids and, as a result, a rapid change in the production of neuroactive steroids may contribute neurodegenerative changes in small nerve fibers of the oral mucosa and/or areas of the brain involved in oral somatic sensations These neuropathic changes are likely to become irreversible as the disease progresses and lead to burning pain, dysgeusia and xerostomia associated with small nerve fiber stomatodynia .More detailsMelyokhin A.I. Psychodynamic aspects of bruxism// https://psy.media/bruksizm/Melekhin A.I. The role of psychological factors in the idiopathic burning mouth syndrome // Collection of abstracts of the Scientific and Practical Conference. XXI century: modern view of mental health - II. - Tashkent, 2022. - pp. 132–136Melyokhin A.I. Psychological factors influencing oral-motor daytime and nighttime parafunctional activity // International scientific and practical conference Problems of mental health during a pandemic: conference materials. - Tula, 2021. - C. 94–101.